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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK1
All Species:
10
Human Site:
Y260
Identified Species:
16.92
UniProt:
Q7Z5N4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q7Z5N4
NP_689957.3
2213
242076
Y260
T
S
D
A
G
A
Y
Y
V
Q
A
V
N
E
K
Chimpanzee
Pan troglodytes
XP_518946
2168
238269
E221
Y
Y
V
Q
A
V
N
E
K
N
G
E
N
K
T
Rhesus Macaque
Macaca mulatta
XP_001105243
2118
232418
V205
S
D
A
G
A
Y
Y
V
Q
A
V
N
E
K
N
Dog
Lupus familis
XP_547004
2144
235913
T224
R
D
V
G
T
P
E
T
M
A
P
V
I
V
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3UH53
2193
240287
Y242
A
S
D
A
G
A
Y
Y
V
Q
A
V
N
E
K
Rat
Rattus norvegicus
XP_001073292
2181
239558
Y230
A
S
D
A
G
A
Y
Y
V
Q
A
V
N
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
V221
P
P
C
N
T
S
V
V
A
G
S
S
E
I
T
Chicken
Gallus gallus
Q8AV58
2169
239459
G221
Q
A
V
N
E
K
N
G
E
N
K
T
S
P
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_686686
2126
234665
A217
P
R
N
T
T
V
V
A
G
I
S
E
A
T
L
Tiger Blowfish
Takifugu rubipres
Q98902
1277
141937
Fruit Fly
Dros. melanogaster
O97394
2224
246236
N235
G
Y
R
A
K
A
I
N
T
Q
L
G
K
E
E
Honey Bee
Apis mellifera
XP_623565
2176
242722
K221
E
E
N
S
P
F
F
K
L
Q
I
T
G
D
A
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
S237
T
D
R
T
I
I
E
S
T
L
P
H
D
E
I
Sea Urchin
Strong. purpuratus
XP_781559
2931
322437
L258
W
Q
K
D
G
E
G
L
D
A
T
G
A
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.7
91.5
86.7
N.A.
89.7
87.3
N.A.
79.6
78.9
N.A.
66
20.5
36.3
36.3
26.1
20.7
Protein Similarity:
100
96.1
93
91.5
N.A.
94
92
N.A.
87.8
87.8
N.A.
79.8
33.5
53.5
53.5
43.8
37.1
P-Site Identity:
100
6.6
6.6
6.6
N.A.
93.3
86.6
N.A.
0
0
N.A.
0
0
26.6
6.6
13.3
6.6
P-Site Similarity:
100
13.3
20
13.3
N.A.
93.3
93.3
N.A.
13.3
13.3
N.A.
13.3
0
33.3
40
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
8
8
29
15
29
0
8
8
22
22
0
15
0
8
% A
% Cys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
22
22
8
0
0
0
0
8
0
0
0
8
8
0
% D
% Glu:
8
8
0
0
8
8
15
8
8
0
0
15
15
36
8
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
15
29
0
8
8
8
8
8
15
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
8
8
8
0
0
8
8
0
8
15
8
% I
% Lys:
0
0
8
0
8
8
0
8
8
0
8
0
8
15
15
% K
% Leu:
0
0
0
0
0
0
0
8
8
8
8
0
0
0
22
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
15
15
0
0
15
8
0
15
0
8
29
0
8
% N
% Pro:
15
8
0
0
8
8
0
0
0
0
15
0
0
8
0
% P
% Gln:
8
8
0
8
0
0
0
0
8
36
0
0
0
0
0
% Q
% Arg:
8
8
15
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
22
0
8
0
8
0
8
0
0
15
8
8
0
0
% S
% Thr:
15
0
0
15
22
0
0
8
15
0
8
15
0
8
15
% T
% Val:
0
0
22
0
0
15
15
15
22
0
8
29
0
8
8
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
15
0
0
0
8
29
22
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _